U.S. EPA Adds 18 New Chemicals to Safer Chemical Ingredients List

On July 21, 2025, the U.S. Environmental Protection Agency (EPA) announced the inclusion of 18 new chemicals into its Safer Chemical Ingredients List (SCIL). This update brings the total number of chemicals on the list to 983, spanning industries such as cleaning agents, industrial solvents, and more.

Under the latest amendments to the Toxic Substances Control Act (TSCA), new chemicals must now undergo EPA safety evaluations before entering the market. The 18 newly listed substances passed rigorous assessments under the Safer Choice Program, exceeding safety standards in human health risk evaluations, ecotoxicological indicators, environmental persistence, and other criteria.

Newly Added Chemicals to SCIL

No.	CAS No.	List Name	TSCA Chemical Name
1	13945-76-1	Lauryl laurate	Dodecanoic acid, dodecyl ester
2	67762-27-0	Cetearyl alcohol	Alcohols, C16-18
3	13257-34-6	Sodium arachidate	Eicosanoic, sodium salt (1:1)
4	71-23-8	Propyl alcohol	1-Propanol
5	29806-73-3	2-Ethylhexyl palmitate	Hexadecanoic acid, 2-ethylhexyl ester
6	123-99-9	Azelaic acid	Nonanedioic acid
7	9067-32-7	Sodium hyaluronate	Hyaluronic acid, sodium salt
8	68648-59-9	Siloxanes and Silicones, di-Me, di-Ph, polymers with Ph silsesquioxanes	Siloxanes and Silicones, di-Me, di-Ph, polymers with Ph silsesquioxanes
9	68915-31-1	Sodium polyphosphates	Polyphosphoric acids, sodium salts
10	110-30-5	N,N'-Ethylenebis(stearamide)	Octadecanamide, N,N'-1,2-ethanediylbis-
11	1592-23-0	Calcium stearate	Octadecanoic acid, calcium salt (2:1)
12	26658-19-5	Sorbitan tristearate	Sorbitan, trioctadecanoate
13	595585-15-2	D-Glucurono-D-gluco-6-deoxy-L-mannan, acetate, calcium magnesium potassium sodium salt	D-Glucurono-D-gluco-6-deoxy-L-mannan, acetate, calcium magnesium potassium sodium salt
14	8013-07-8	Epoxidized soybean oil (ESBO)	Soybean oil, epoxidized
15	61791-00-2	Ethoxylated tall oil fatty acids	Fatty acids, tall-oil, ethoxylated
16	141-97-9	Ethyl acetoacetate	Butanoic acid, 3-oxo-, ethyl ester
17	93334-37-3	Oils, palm, stearins, hydrogenated	Palm oil, stearins, hydrogenated
18	68514-74-9	Hydrogenated palm oil	Palm oil, hydrogenated

As part of the environmental pillar of the Powering the Great American Comeback initiative, the SCIL update coincides with enhancements to a digital query platform. Businesses can now compare chemical safety levels using a three-color labeling system, while consumers can scan product QR codes to access ingredient traceability data. The EPA aims to achieve full smart traceability coverage for certified products by 2026.

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Further Information

EPA

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