U.S. EPA Announces Addition of PFHxS-Na to the Toxic Release Inventory (TRI)

On October 7, 2025, the U.S. Environmental Protection Agency (EPA) announced that, under the automatic listing mechanism of the National Defense Authorization Act for Fiscal Year 2020 (NDAA), sodium perfluorohexanesulfonate (PFHxS-Na, CAS RN 82382-12-5) has been formally added to the Toxic Release Inventory (TRI). The listing will take effect on January 1, 2026. With this addition, the total number of PFAS subject to TRI reporting has increased to 206.

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Background

PFHxS-Na is a common surfactant used in processes such as firefighting foam, metal plating, and semiconductor cleaning. It is persistent, bioaccumulative, and potentially hepatotoxic. In 2025, the EPA released the IRIS Toxicological Review: Perfluorohexanesulfonic Acid (PFHxS, CAS RN 335-46-4) and Related Salts, which for the first time established toxicity values for PFHxS-Na. Although the TRI list previously included PFHxS and other associated salts, PFHxS-Na was not covered.

Recently Added PFAS

CASRN	TRI Chemical Name	Effective Reporting Year	Triggering Activity
307-24-4	Perfluorohexanoic acid	2024	Final Toxicity Value
422-64-0	Perfluoropropanoic acid	2024	Final Toxicity Value
2923-26-4	Sodium perfluorohexanoate	2024	Final Toxicity Value
21615-47-4	Ammonium perfluorohexanoate	2024	Final Toxicity Value
82113-65-3	1,1,1-Trifluoro-N-[(trifluoromethyl)sulfonyl] methanesulfonamide	2024	Final Toxicity Value
90076-65-6	Lithium bis[(trifluoromethyl)sulfonyl] azanide	2024	Final Toxicity Value
2816091-53-7	Betaines, dimethyl(γ-ω-perfluoro-γ-hydro-C8-18-alkyl)	2024	CBI Declassification
377-73-1	Perfluoro-3-methoxypropanoic acid	2025	Final Toxicity Value
3108-42-7	Ammonium perfluorodecanoate (PFDA NH4)	2025	Final Toxicity Value
3830-45-3	Sodium perfluorodecanoate (PFDA-Na)	2025	Final Toxicity Value
27619-97-2	6:2 Fluorotelomer sulfonate acid	2025	Final Toxicity Value
425670-75-3	6:2 Fluorotelomer sulfonate anion	2025	Final Toxicity Value
59587-38-1	6:2 Fluorotelomer sulfonate potassium salt	2025	Final Toxicity Value
59587-39-2	6:2 Fluorotelomer sulfonate ammonium salt	2025	Final Toxicity Value
27619-94-9	6:2 Fluorotelomer sulfonate sodium salt	2025	Final Toxicity Value
3030471-22-5	Acetic acid, [(γ-ω-perfluoro-C8-10-alkyl)thio] derivs., Bu esters	2025	CBI Declassification
82382-12-5	Sodium perfluorohexanesulfonate (PFHxS-Na)	2026	Final Toxicity Value

Note: All PFAS added to the TRI can be accessed via the following link:

https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.epa.gov%2Fsystem%2Ffiles%2Fdocuments%2F2024-01%2Flist-of-pfas-added-to-the-tri-by-the-ndaa.xlsx&wdOrigin=BROWSELINK

Starting January 1, 2026, relevant enterprises must begin tracking the use and handling of PFHxS-Na in accordance with Section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA) and submit their first annual report by July 1, 2027.

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Further Information

US EPA

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