On Aug 24, 2026, Japan's MHLW opened public comment on a draft ordinance amending the Industrial Safety and Health Ordinance, due Sept 23, 2026.

On June 22, 2026, MHLW, METI and MOE jointly promulgated an amendment to the Ordinance on Public Notice of Names of New Chemical Substances.

Japan’s METI updated FY2026 guidelines for CSCL Small Amount and Low Tonnage confirmation routes. Starting with the fourth FY2026 application batch, electronic submissions must use G Biz ID (Prime or Member accounts) as legacy applicant codes are discontinued. Manufacturers and importers should immediately obtain accounts, check filing windows, and upgrade submission systems.

On March 31, 2026, Japan's MHLW issued a notification amending the "List of Substances Requiring Indicated Measures" under the ISHA.

Japan has added 36 substances to the mandatory labeling and SDS list under the Industrial Safety and Health Act.

On July 3, 2026, Japan's NITE released the FY2025 three-ministry GHS classification results covering 142 substances (59 newly classified and 83 reclassified).

Recently, Japan's Fire and Disaster Management Agency (FDMA) issued a notification: as PFHxS (perfluorohexane sulfonic acid)-related substances have been designated as Class I Specified Chemical Substances under the Chemical Substances Control Law (CSCL), concerned parties should check whether the fire extinguishers and extinguishing agents they hold contain such substances, and handle them properly in accordance with the newly revised technical standards.

Japan designated multiple chemical substances as Class I Specified Chemical Substances.

China announced that 20 Japanese entities have been added to the export control list.

Japan included perfluorohexanesulfonic acid (PFHxS) and its related substances under strict regulatory control.