On March 31, 2026, Japan's MHLW issued a notification amending the "List of Substances Requiring Indicated Measures" under the ISHA.

Japan has added 36 substances to the mandatory labeling and SDS list under the Industrial Safety and Health Act.

On July 3, 2026, Japan's NITE released the FY2025 three-ministry GHS classification results covering 142 substances (59 newly classified and 83 reclassified).

Recently, Japan's Fire and Disaster Management Agency (FDMA) issued a notification: as PFHxS (perfluorohexane sulfonic acid)-related substances have been designated as Class I Specified Chemical Substances under the Chemical Substances Control Law (CSCL), concerned parties should check whether the fire extinguishers and extinguishing agents they hold contain such substances, and handle them properly in accordance with the newly revised technical standards.

Japan designated multiple chemical substances as Class I Specified Chemical Substances.

China announced that 20 Japanese entities have been added to the export control list.

Japan included perfluorohexanesulfonic acid (PFHxS) and its related substances under strict regulatory control.

JSA released the revised Japanese Industrial Standards JIS Z 7252:2025 and JIS Z 7253:2025.

Japan announced that a cabinet order to partially amend the Enforcement Order of the CSCL has been approved.

Japan issued the schedule for submitting manufacturing and import notifications for low-volume new chemical substances for fiscal year 2026.