Japan’s Ministry of Health, Labour and Welfare (MHLW) is updating the Industrial Safety and Health Act (ISHA) to mandate SDS and labeling compliance for 35 newly added substances, 1 deletion, and 4 modified entries. Following October 2026 overseas stakeholder hearings, affected chemical exporters must review product inventories ahead of the April 2029 enforcement date.

Japan’s MHLW, METI, and MOEJ released a collection of CSCL violation cases and countermeasures. To ensure compliance, companies must complete mandatory filings and lead times before manufacturing or importing new chemicals, centralize volume tracking, establish strong cross-departmental and supply-chain controls, and conduct regular internal audits.

Japan's MHLW, METI, and MOE set a 2027 CSCL notification schedule: 10 rounds, first deadline Oct 6, 2026, via the NITE system.

On Aug 24, 2026, Japan's MHLW opened public comment on a draft ordinance amending the Industrial Safety and Health Ordinance, due Sept 23, 2026.

On June 22, 2026, MHLW, METI and MOE jointly promulgated an amendment to the Ordinance on Public Notice of Names of New Chemical Substances.

Japan’s METI updated FY2026 guidelines for CSCL Small Amount and Low Tonnage confirmation routes. Starting with the fourth FY2026 application batch, electronic submissions must use G Biz ID (Prime or Member accounts) as legacy applicant codes are discontinued. Manufacturers and importers should immediately obtain accounts, check filing windows, and upgrade submission systems.

On March 31, 2026, Japan's MHLW issued a notification amending the "List of Substances Requiring Indicated Measures" under the ISHA.

Japan has added 36 substances to the mandatory labeling and SDS list under the Industrial Safety and Health Act.

On July 3, 2026, Japan's NITE released the FY2025 three-ministry GHS classification results covering 142 substances (59 newly classified and 83 reclassified).

Recently, Japan's Fire and Disaster Management Agency (FDMA) issued a notification: as PFHxS (perfluorohexane sulfonic acid)-related substances have been designated as Class I Specified Chemical Substances under the Chemical Substances Control Law (CSCL), concerned parties should check whether the fire extinguishers and extinguishing agents they hold contain such substances, and handle them properly in accordance with the newly revised technical standards.