On November 10, 2025, the U.S. Environmental Protection Agency (EPA) has announced a significant proposal to adjust reporting rules for per- and polyfluoroalkyl substances (PFAS) under the Toxic Substances Control Act (TSCA). If finalized, manufacturers would no longer need to submit complex data to the EPA for four key categories: low-concentration scenarios, imported articles, byproducts/impurities, and small-scale research and development (R&D) uses.

On November 9, 2025, China's Ministry of Commerce (MOFCOM) officially released Announcement No. 72 of 2025, announcing the suspension of the provisions of Article 2 of MOFCOM Announcement No. 46 of 2024 (Announcement on Strengthening Export Controls on Certain Dual-Use Items to the United States), effective immediately until November 27, 2026.

On October 7, 2025, the U.S. Environmental Protection Agency (EPA) announced that, under the automatic listing mechanism of the National Defense Authorization Act for Fiscal Year 2020 (NDAA), sodium perfluorohexanesulfonate (PFHxS-Na, CAS RN 82382-12-5) has been formally added to the Toxic Release Inventory (TRI). The listing will take effect on January 1, 2026. With this addition, the total number of PFAS subject to TRI reporting has increased to 206.

This update brings the total number of chemicals on the list to 983.

The updated TSCA Inventory now includes 86,862 chemical substances, with 42,578 classified as Active.

On May 14, 2025, the U.S. Environmental Protection Agency (EPA) announced on its decision to retain the existing Maximum Contaminant Levels (MCLs) for perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in drinking water established in 2024, while extending the compliance deadline for public water systems from 2029 to 2031. Concurrently, the agency proposed to revoke standards for PFHxS, PFNA, HFPO-DA (GenX chemicals), and PFBS mixtures, initiating a re-evaluation process. A new "PFAS OUT Program" was unveiled to bolster technical support.

On June 20, 2025, the U.S. Environmental Protection Agency (EPA) released the final risk assessment for 1,1-dichloroethane under the Toxic Substances Control Act (TSCA). The assessment concludes that 1,1-dichloroethane poses an unreasonable risk of injury to human health under three conditions of use (COUs), but does not present significant risks to the general public or the environment.

On June 4, 2025, the US Environmental Protection Agency (EPA) signed a final rule to extend the deadline for submitting health and safety data for 16 designated chemical substances under the Toxic Substances Control Act (TSCA) to May 22, 2026, to give the relevant industries more time to prepare for compliance.

On May 21, 2025, the New Hampshire State Senate and House of Representatives amended the RSA 149-M:64 regulation, introducing a new ban that explicitly prohibits the sale of ski wax, boat wax, surfboard wax, and similar sports products containing intentionally added per- and polyfluoroalkyl substances (PFAS).

On May 13, 2025, the US Environmental Protection Agency (EPA) announced significant adjustments to the data submission deadlines under the Toxic Substances Control Act (TSCA) for per- and polyfluoroalkyl substances (PFAS) and PFAS-containing products.