South Korea's NICS has pre-announced plans to designate 38 chemicals as acute-toxic, chronic-toxic, or ecotoxic substances under K-REACH.

South Korea’s Ministry of Climate, Energy and Environment (MCEE) implemented an early emergency registration process under K-REACH (Act on Registration and Evaluation of Chemical Substances). Designed to mitigate global supply chain disruptions caused by Middle East tensions, this fast-track pathway allows companies to import critical raw material substitutes—such as naphtha and petrochemical feedstocks—without waiting months for full toxicology clearance.

On April 24, 2026, the Chemical Accident Prevention Division of South Korea's MoEL released the latest revision of the Korean GHS regulation.

South Korea amended to the Enforcement Decree of the Act on Registration and Evaluation of Chemical Substances.

MCEE issued Notice No. 2026-103 revising the Existing Chemical Substances List.

From July 1, 2026, newly prepared MSDS or changes to existing MSDS must use the revised format.

On March 27, 2026, South Korea's National Institute of Chemical Safety (NICS) issued Notice No. 2026-5, revising the Designation of Acute Human Hazardous Substances, Chronic Human Hazardous Substances, and Ecological Hazardous Substances under the Act on Registration and Evaluation of Chemicals (K-REACH) and its Enforcement Decree. The previous revision was completed on 7 August 2025.

Korea National Institute of Chemical Safety (NICS) issued Announcement No. 2026-1, officially amending the Chemical Hazard Assessment Results.

Pursuant to partial revisions of the Enforcement Rule of the Act on Registration and Evaluation of Chemicals (K-REACH) announced on October 15, 2025, the National Institute of Chemical Safety (NICS) released a notice on December 17 regarding the procedure for changing the registration entity, specifically the OR change process, within its system.

South Korea issued the Designation Notice of Human, etc. Hazardous Substances.