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Recently, the European Commission’s novel food status has updated the information regarding S-adenosyl-L-methionine disulfate tosylate (also referred to as Sadenosyl-L-methionine disulfate p-toluenesulfonate). According to the latest novel food status, this ingredient has now been recognized as a novel food.

The food enzyme amidase (acylamide amidohydrolase, EC 3.5.1.4) is produced with the genetically modified Escherichia coli strain SP-a by c-LEcta GmbH. The genetic modifications did not give rise to safety concerns.

To help companies clearly understand the international compliance status of NMN, CIRS Group will summarize the application approval status of NMN in the EU, the US, and Australia for reference.

The acute exposure assessment was conducted on a single‑consumption‑event basis considering the reported use levels and analytical data of glycerol in slush ice drinks and the proposed maximum level of 50,000 mg glycerol/L in de-alcoholised wine. The Panel considered that a conservative dose above which unintended pharmacological effects would occur should be used for the determination of the acute reference dose (ARfD). Based on Wald and McLaurin (1982) study, the Panel derived an ARfD of 125 mg glycerol/kg body weight for a single consumption event.

CIRS EU, the European subsidiary of CIRS Group, will be exhibiting at Vitafoods Europe in Barcelona, Spain, from May 5–7, 2026 (Booth No.: 6D84M, Hall 6) . CIRS has participated in Vitafoods Europe multiple times in Geneva, and attended the 2025 event in Barcelona. This year, we will once again be present at Vitafoods Europe 2026. We sincerely invite both new and existing partners to join us for discussions and to explore collaboration opportunities together. We look forward to seeing you there.

At the request of the European Commission, the Panel on Nutrition, Novel Foods, and Food Allergens (NDA) of the European Food Safety Authority (EFSA) was tasked with providing an opinion on the use of carbon dioxide extract from Cannabis sativa L. as a novel food under Regulation (EU) 2015/2283.

CIRS Group has compiled and summarized the intended uses and use levels of HMOs approved in the EU for industry reference. Among them, chemically synthesized and microbially produced 2’-FL have identical scope of use and use levels; similarly, chemically synthesized and microbially produced LNnT share the same conditions of use. The remaining HMOs are produced via microbial sources, and their intended uses may vary depending on the production organism.

Since the UK’s withdrawal from the EU in 2021, food substances that have obtained EU marketing authorization have been required to undergo additional UK specific notifications to enter the UK market (for example, novel foods already approved in the EU cannot enter the UK market in compliance without resubmitting a notification to UK authorities) . However, in May 2025, the UK government reached an agreement with the EU to advance a new Sanitary and Phytosanitary (SPS) Agreement (hereinafter referred to as the “UK-EU SPS Agreement”). The agreement covers the trade, production, and transport of animals, plants, and related products; food and feed safety; pesticide regulation; and more, aiming to streamline the flow of goods between the UK and the EU. It is scheduled to officially enter into force in mid-2027.

In January 2026, the European Food Safety Authority released updated scientific guidance and administrative guidance for food additive authorisation applications. These updates reflect recent technological advancements in food additives. Compared with previous versions, the new guidance improves both comprehensiveness and clarity, offering more specific and actionable instructions.