As of December 31, 2025, according to the public information of the EU information retrieval platform Open EFSA, CIRS has conducted statistical analysis on the approval trends of Novel Food (hereinafter referred to as NF) in the EU in the fourth quarter of 2025.

On November 27, 2025, EFSA updated a series of administrative guidance regarding novel food, food improvement agents (including food additives, food enzymes and food spices), and feed additives. This update was not only a mere streamlining of application procedures, but a signal for EU to raising regulatory requirements.

On December 17, 2025, the Official Journal of the European Union published the European Commission's guidance document for the implementation of Commission Regulation (EU) 2024/3190.

Nicotinamide Mononucleotide (NMN) is currently undergoing regulatory authorization processes in multiple major global markets. To help companies clearly understand the international compliance status of NMN, CIRS has summarized recent regulatory developments in the United States, Australia, and the European Union for reference.

On 3 November 2025, EFSA released its safety evaluation report on synthetic cannabidiol (CBD) as a novel food. According to the assessment conducted by EFSA’s expert panel, the safety of the NF synthetic CBD cannot be established.

According to Regulation (EC) No 1831/2003 (Feed Additives Regulation), feed additives refer to substances, microorganisms, or preparations—other than feed materials and premixes—that are intentionally added to feed or water to perform one or more functions. The EU has established a positive list of feed additives. To market a new feed additive not included in the positive list, an application for authorization must first be submitted to the EU authorities. Each authorization is valid for 10 years and may be renewed for an additional 10 years.

As of September 30, 2025, according to the public information of the EU information retrieval platform Open EFSA, CIRS has conducted statistical analysis on the approval trends of Novel Food (hereinafter referred to as NF) in the EU in the third quarter of 2025.

Influenced by globalization and strategic development, an increasing number of companies applying for novel food are expanding their target market, with the EU being one of the most popular destinations. Whether it is the application for new food ingredients/additives/enzymes or for new feed ingredients/additives, companies are required to conduct a series of tests. The EU, under its transparency regulations, requires companies to submit pre-notifications of tests before conducting them—this is a unique EU requirement. Failure to notify in advance without a valid justification may result in delays or penalties in the application process. In this article, CIRS Group provides an introduction for companies on EU pre-notification requirements for applications.

Nicotinamide mononucleotide (NMN) is a bioactive nucleotide naturally present in the human body and serves as a key precursor for synthesizing nicotinamide adenine dinucleotide (NAD+) in mammals. NAD+ plays a vital role in human health, participating in thousands of biochemical reactions. As people age, their nicotinamide adenine dinucleotide (NAD+) levels decrease, where depletion is associated with downregulation of energy production. NMN, a precursor to NAD+, reportedly slows the process by elevating NAD+levels in the body.

Styrene is a chemical used in the production of plastic materials and items. In the EU, it is authorised for use in food packaging that is in direct contact with food.