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European Union
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EFSA has published its scientific opinion on the safety assessment of lacto-N-triose II (LNTri II) as a novel food. The Panel concluded that LNTri II does not raise safety concerns under the proposed conditions of use and use levels.
In H1 2026, the EU approved 8 food additive modifications, validated 5 dossiers, and published 9 scientific opinions. While new plant- and microorganism-derived additives are gaining interest, modification requests remain dominant. Amid strict upcoming EFSA guidance revisions, applicants must ensure complete, robust dossiers to ensure efficient market authorization.
Based on publicly available information from the Open EFSA and regulations issued by the European Commission, CIRS conducted a statistical analysis of the EU Novel Food (NF) approval dynamics in the first half of 2026 for enterprise reference.
The EFSA Panel on Food Contact Materials (FCM) assessed the safety of the Bandera Twin recycling process (EU register number RECYC341).
The food enzyme dextransucrase (sucrose:1,6-α-d-glucan 6-α-d-glucosyltransferase; EC 2.4.1.5) is produced with the genetically modified Bacillus subtilis strain DP-Eyp97 by Genencor International B.V. The production strain met the requirements for the qualified presumption of safety. The food enzyme was considered free from viable cells of the production organism and its DNA.
Recently, the European Commission’s novel food status has updated the information regarding S-adenosyl-L-methionine disulfate tosylate (also referred to as Sadenosyl-L-methionine disulfate p-toluenesulfonate). According to the latest novel food status, this ingredient has now been recognized as a novel food.
The food enzyme amidase (acylamide amidohydrolase, EC 3.5.1.4) is produced with the genetically modified Escherichia coli strain SP-a by c-LEcta GmbH. The genetic modifications did not give rise to safety concerns.
To help companies clearly understand the international compliance status of NMN, CIRS Group will summarize the application approval status of NMN in the EU, the US, and Australia for reference.
The acute exposure assessment was conducted on a single‑consumption‑event basis considering the reported use levels and analytical data of glycerol in slush ice drinks and the proposed maximum level of 50,000 mg glycerol/L in de-alcoholised wine. The Panel considered that a conservative dose above which unintended pharmacological effects would occur should be used for the determination of the acute reference dose (ARfD). Based on Wald and McLaurin (1982) study, the Panel derived an ARfD of 125 mg glycerol/kg body weight for a single consumption event.